Fluidized bed granulator BFS

for the pharmaceutical industryR&Ddryer

Fluidized bed systems have been used in the pharmaceutical industry for many decades. Adding an aqueous or alcoholic granulation medium compresses the mixture of dry powder particles. The fluid contains a volatile solvent which can be removed by drying. For a long time, fluidized bed solutions were dominated by top-spray. However, the benefits of systems with tangential spray nozzles have become more apparent, thus tending to take over top-spray granulators. L.B. Bohle’s fluid bed granulation portfolio includes R&D systems for small production volumes as well as production scale systems. L.B. Bohle uses the Bohle Uni Cone BUC® process to optimize fluidized bed The patented Bohle Uni Cone BUC® is a specially slotted air distributor plate with a conical displacement cone. This design allows for a complete fluidization of the particles. This tangential particle motion achieves a uniform film, e.g. on pellets, without any twins. Since the fluidized particles or granules move tangentially at relatively low fluidization height, they do not require a high-volume expansion. This reduces the required installation height, saving costs and production floor space. At least six filter elements of the BFS, that can be cleaned separately, ensure that the air flow though the product bed is uninterrupted. Drying, granulation and coating without need for alteration Another advantage of the tangential design in facilities from L.B. Bohle is that granulation, coating and drying can be carried out in a single system without having to reconfigure the equipment.