The paradigm change from batch production to continuous manufacture requires a new approach for the production processes used, as well as for the required automation technology.
Comprehensive initiatives for quality increase – mainly driven by the FDA – strongly focuses on continuous manufacturing for manufacture of solid drugs.
The ability to monitor a production process more closely using PAT, and to consistently produce high-quality products as a result, is the central aspect of this initiative.
- Higher patient safety
- Lower costs
- Better process understanding
- Optimised process control
As the most innovative technology company for machines and processes for the pharmaceutical solids production, L.B. Bohle supplies comprehensive solutions for continuous manufacturing with a high development speed.
Modular design: Direct compression, wet granulation, and dry granulation
The QbCon® continuous manufacturing systems allows for production of pharmaceutical solids from powder to the coated tablet with a throughput from 5 to 25 kg/h. QbCon® stands out with its modular design that ensures maximum flexibility and efficiency for the customer.
QbCon® enables three production processes:
Continuous direct compression
Continuous wet granulation
Continuous dry granulation