Cervical cancer test kit LCMHP02

oncologyfor genesHPV

HPV 6/11/16/18 Detection Kit provides reagents to perform assays for 48 tests Technical information Real-Time PCR Assay for Detection of 2 High-risk HPVs and 2 low-risk HPVs Human papillomavirus (HPV) is a sexually transmitted DNA virus that establishes infection in squamous epithelialcells in the human body. There are more than 200 types of HPV, which can be classified into high or low-risktypes depending upon their oncogenic potentials.High-risk HPVs also called oncogenic HPVs, which have been confirmed to cause cancer. Low-risk HPVs can cause genital warts and low-grade changes in thecells, but rarely cause cancer. The most common HPV types that infect the human body are HPV types 6, 11, 16 and 18. HPV6 and HPV11 are most commonly associated with benign lesions such as genital warts and mild dysplasia of the cervix. HPV16 and HPV18 are known to cause around 70% of cervical cancer cases. Currently there is HPV quadrivalent vaccine that could protect against HPV types 6, 11, 16 and 18, and is recommended primarily for those women not yet having been exposed to HPV. Intended Use: The kit is intended for qualitative detection of two high-risk HPV types 16/18 and two low-risk HPV types 6/11. Technological Principles: The kit is designed for a specific amplification of L1 gene in HPV DNA. The targeted region of HPV DNA is amplified by several specific primers and detected by novel fluorescence probes. A non-rivalry internal control is added in the HPV DNA detection system to reveal the presence of PCR inhibitors and monitor the accuracy of experimental operation.