Solution reagent kit respiraRNA 3.0

diagnosticRT-qPCRliquid

The respiraRNA 3.0 real time RT-PCR Kit is an assay for the simultaneous detection of RNA of Influenza A Virus, RSV, Influenza B Virus extracted from biological specimens. 2 Pathogen Information Influenza viruses belong to the family of Orthomyxoviridae and are the causative agent of ‘the flu‘. Influenza A and B viruses have a single stranded RNA genome, consisting of 8 RNA segments. The genome of Influenza A Viruses is characterized by a high mutation frequency, the so-called ‚antigenic drift‘. Numerous subtypes of Influenza A Viruses are known. They can be catergorized by their surface antigens H (haemagglutinin) and N (neuraminidase): Influenza A (H1N1) Virus, Influenza A (H5N1) Virus etc. Therefore, yearly in silico analysis of the sequences of newly emerged subtypes is done, to prevent false negative results caused by primer and/or probe mismatches. Respiratory Syncytial Viruses are enveloped negative-sense, single stranded RNA Viruses of the Paramyxoviridae familiy. RSV is a member of the subfamily Pneumovirinae, genus Pneumovirus. RSV are divided into subgroups A and B. RSV is a virus that causes infections of the lungs and respiratory tract. It's so common that most children have been infected with the virus by age 2. RSV can also infect adults. In adults and older, healthy children, the symptoms of RSV infections are mild and typically mimic the common cold. Self-care measures are usually all that's needed to relieve any discomfort. Infection with RSV can be severe in some cases, especially in premature babies and infants with underlying health conditions.