Solution reagent kit G01020-32

diagnosticRT-qPCRliquid

The diarellaPanLegionella real time PCR TM is an assay for the detection of Legionella spp. DNA in clinical specimens (e.g. throat swabs, nasal swabs, bronchial lavage) and environmental samples (e.g. water samples). 2 Pathogen Information Legionella are widespread environmental germs which occur in natural and also artificial water carrying sources, such as plumbing fixtures and potable water systems. They also are able to infect protozoans and subsequently reproduce within these organisms. Temperatures between 30°C and 50°C and the ability to subsequently reproduce within these organisms increase their growth. From their natural habitat, Legionella are sometimes placed in the man-made water systems. Consequently, Legionella are also prevalent in anthropogenic waters such as potable water, cooling tower reservoirs, and whirlpools. Aerosol-generating systems such as faucets, showerheads, cooling towers, and nebulizers aid in the transmission of Legionella from water to air. Human inhalation of contaminated aerosols leads to Legionella infections and disease outbreaks. Infection from inhaling airborne water droplets or mist containing viable Legionella, which are small enough to pass deep into the lungs and be deposited in the alveoli, the small pockets in the lungs. The bacteria rapidly reproduce within the macrophages. Although healthy individuals may develop Legionnaires Disease, people thought to be at increased risk of infection include smokers, patients with chronic respiratory diseases and any immunosuppressed condition. Initial symptoms of Legionnaires Disease include high fever, chills, headache and muscle pain.