Solution reagent kit diarellaRickettsia

diagnosticfor RT-PCRliquid

The diarellaRickettsia real time PCR is an assay for the amplification of purified DNA of Rickettsia species, extracted from biological specimens. 2 Background Information Rickettsia is a genus of bacteria of the tribe Rickettsiae, made up of small, gramnegative, rod-shaped to coccoid, often pleomorphic microorganisms, which multiply only in host cells. Organisms occur in the cytoplasm of tissue cells or free in the gut lumen of lice, fleas, ticks, and mites and are transmitted by their bites. R. conorii is the etiologic agent of Boutonneuse Fever (a tickborne disease endemic in the Mediterranean area, Crimea, Africa, and India with chills, fever, primary skin lesion (tache noire), and rash appearing on the second to fourth day). R. prowazekii is transmitted between humans by the human body louse and from flying squirrels to humans by fleas and lice. R. prowazekii is the agent of epidemic typhus and Brill-Zinsser disease. Epidemic typhus is a form of typhus so named because the disease often causes epidemics following wars and natural disasters. The Brill-Zinsser disease is characterized by a delayed relapse of epidemic typhus. After a patient contracts epidemic typhus from the fecal matter of an infected louse (Pediculus humanus), the rickettsia can remain latent and reactivate months or years later, with symptoms similar to or even identical to the original attack of typhus, including a maculopapular rash. R. typhi is the cause of murine typhus, which is transmitted to humans chiefly by rat fleas. Murine typhus is a mild, acute, endemic form of typhus characterized by fever, headache, and muscular pain.