Solution reagent kit diarellaEhrlichia

diagnosticfor RT-PCRliquid

The diarellaBorrelia/Rickettsia real time PCR is an assay for the detection of Borrelia burgdorferi sensu lato DNA and Rickettsia species DNA, extracted from biological specimens incl. ticks. 2 Pathogen Information Borrelia are gram-negative bacteria of the spirochaete family. Members of the genus Borrelia are the causative agents of two important tick-borne diseases: relapsing fever and Lyme disease. In Europe, Lyme borreliosis is the most common vector-borne disease. The highest incidence is reported from Austria, Switzerland, the Czech Republic, Germany, Slovenia, as well as from the northern countries bordering the Baltic Sea. Lyme borreliosis is a multi-system disorder, which can lead to severe complications of the neurological system, the heart and the joints. At an early stage of its manifestation borreliosis is treatable with antibiotics, however, clinical diagnosis is complicated. Antibodies are not detectable in the blood until weeks after infection and symptoms are highly variable. Rickettsia is a genus of bacteria of the tribe Rickettsiae, made up of small, gramnegative, rod-shaped to coccoid, often pleomorphic microorganisms, which multiply only in host cells. Organisms occur in the cytoplasm of tissue cells or free in the gut lumen of lice, fleas, ticks, and mites and are transmitted by their bites. R. conorii is the etiologic agent of Boutonneuse Fever (a tickborne disease endemic in the Mediterranean area, Crimea, Africa, and India with chills, fever, primary skin lesion (tache noire), and rash appearing on the second to fourth day).