Solution reagent kit 1121005
diagnosticliquidcreatine kinase

solution reagent kit
solution reagent kit
solution reagent kit
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Characteristics

Type
solution
Applications
diagnostic
Format
liquid
Tested parameter
creatine kinase
Method
immunologic
Storage temperature

Max.: 8 °C
(46 °F)

Min.: 2 °C
(36 °F)

Description

The major CK activity in normal serum is due to CK-MM and CKMB isoenzymes, found mainly in skeletal and heart muscle. CK-BB is ussualy present in serum at low concentration. Both, creatine kinase (CK) enzymes are dimers formed by the association of two sub-units from muscle (M) and nerve cells (B). The immunoinhibition from an specific antibody of both, MM subunits and the single M sub-unit of CK-MB, allows the determination of the B sub-unit. The CK-B activity corresponding to half of CK-MB is measured by the increasing rate of absorbance resulting from the following coupled reactions.

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