This monoclonal antibody enables specific detection of human IgG2 in antigen-specific ELISA.
Recommendation
HP6200 is recommended in antigen-specific ELISA.
Product details
Product - Anti-human IgG2 mAb (HP6200), unconjugated
Conjugate - Unconjugated
Immunogen - Native human IgG2
Host - Mouse
Reactivity - Human
Cross-reactivity - No cross-reactivity (less than 0.1%) with human IgG1, IgG3, IgG4, IgA, IgE, IgM or with IgG from mouse, rat, goat, rabbit, and cow. Less than 1% cross-reactivity with IgG from rhesus and cynomolgus macaque.
Purification - Purified from in vitro cultures by protein G affinity chromatography.
Concentration - 0.5 mg/ml
Supplied in - PBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).
Contents - Monoclonal antibody HP6200, unconjugated. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.
Analyte description
Immunoglobulin G (IgG) is the most abundant Ig isotype in serum, making up approximately 80% of all serum Immunoglobulins. In humans, there are four subclasses of IgG, with the highest serum concentrations of IgG1 followed by IgG2, IgG3, and IgG4. IgG2 is a poor activator of Fc receptors.