Monoclonal antibody MT3B3

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This monoclonal antibody enables specific detection of bovine IL-2 in immunoassays such as ELISpot, FluoroSpot, and ELISA. Recommendation MT3B3 is recommended as detection mAb in ELISpot, FluoroSpot, and ELISA in combination with capture mAb MT11A31 (product code 3111-3). Product details Analyte - IL-2 Conjugate - Biotin Immunogen - Recombinant bovine IL-2 Host - Mouse Reactivity - Cow Specificity - Native and recombinant bovine (cow) IL-2 Cross-reactivity - Cross-reacts with IL-2 from sheep. For more information please check the Cross-reactivity guide section below. Purification - Purified from in vitro cultures by protein G affinity chromatography. Biotinylation - Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin. Concentration - 0.5 mg/ml Supplied in - Protein-containing buffer with 0.02% sodium azide. Contents - Monoclonal antibody MT3B3, biotinylated. Supplied at 0.5 mg/ml in a protein containing buffer with 0.02% sodium azide Veterinary reagents Species reactivities of our veterinary assays and included monoclonal antibodies are summarized in the tables below. Analyte description Interleukin 2 (IL-2) is predominantly produced by activated T cells. IL-2 promotes the proliferation, differentiation, and survival of antigen-activated T cells and NK cells. After antigen stimulation, the cytokine also promotes the differentiation of T cells into effector and memory T cells. Therefore IL-2 plays an important role in the body's response to infection. IL-2 is also key to tolerance, as it promotes the differentiation of certain immature T cells into regulatory T cells in the thymus, ultimately preventing autoimmune diseases.