Radial-arm experiment maze Escape Hole

for animal researchfor micefor rats

Description This modification of the radial arm maze combines the best elements of the Radial arm maze with the fear aversion motivation of the Barnes maze. Originally described by Paganelli et al (2004) in a murine model of cerebral ischemia, the device is a sensitive and well-designed apparatus for evaluation of learning and memory. All 8 arms have holes in which rodents can seek escape, but of the 8 arms, only one contains true refuge; the remaining arms have goal boxes that are open-ended. Rails (2.5 cm high) borders each arm to prevent the animal from falling. The rotatable maze was elevated 90 cm above the floor on a metal stand, similar to the Barnes maze to shift extramaze cues.