removes a high molecular weight components from plasma. Immonoglobulin, cryoglobulin, low-density-lipoprotein, viruses are involved in inflammatory, autoimmune diseases and similar forms with acute or chronic decourse.
Cascade Filtration (CF) consists of a double filter system with the advantages of a selective removal without infusion of exogenous fluids. The separated plasma is pumped into a hollow fibers filter with a different nominal cut-off. The CF is effective in the cast nephropathy, in Waldenstrom’s macroglobulinemia, in active cryoglobulinemia. CF is used successfully in Guillain-Barrè Syndrome (GBS), Myasthenia Gravis (MG), hypercholesterolemia, Focal Segmental Glomerulosclerosis (FSCS) and recently in the Age-related Macular Degeneration (AMD), Lupus Erythematosus, rhabdomyolysis, acute renal failure due to Multiple Myeloma and others.