Celiac disease test kit CeliAK IgG LINE
IgGserumline immunoassay

Celiac disease test kit - CeliAK IgG LINE  - MEDIPAN GmbH - IgG / serum / line immunoassay
Celiac disease test kit - CeliAK IgG LINE  - MEDIPAN GmbH - IgG / serum / line immunoassay
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Characteristics

Applications
celiac disease
Tested parameter
IgG
Sample type
serum
Analysis mode
line immunoassay
Format
strip
Result display time

80 min

Description

The CeliAK IgG LINE is a qualitative line immunoassay for the determination of IgG antibodies against deamidated gliadin (d-gliadin) and tissue transglutaminase (tTG) in human serum. The CeliAK IgG LINE is intended as an aid in the diagnosis of celiac disease in conjunction with other clinical and laboratory findings. The immunoassay is designed for manual professional in vitro diagnostic use. Diagnostic Relevance Celiac disease or gluten-sensitivity is characterized by small intestinal damages leading to a so-called “flat” mucosa. Due to this extensive lesions, malabsorption occurs frequently accompanied with a depletion of key nutrients. The alcohol soluble fraction of gluten, gliadin, a substrate of tissue transglutaminase (tTG), represents a causative agent of celiac disease, by stimulating an inflammatory process in the small intestine. Serological method of celiac disease diagnosis includes the detection of IgA and IgG antibodies to tissue transglutaminase and deamidated gliadin. IgA antibodies to tissue transglutaminase are considered to have the highest predictive value, thus patients suffering from IgA deficiency, a frequent concomitant disease in celiac patients, can be diagnosed using IgG type antibodies. Indication - Celiac disease Description - Line immunoassay for the qualitative determination of IgG antibodies against deamidated gliadin and tissue transglutaminase in human serum Format - Test strips coated with highly purified deamidated gliadin and tissue transglutaminase Total incubation time - 80 min. Sample volume - 10 µL serum No. of determinations - 20 x 2

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