Rheumatic disease test kit ANA 18 LINE

IgGserumline immunoassay

The ANA 18 LINE is a qualitative line immunoassay for the determination of IgG antibodies against nuclear and cytoplasmic antigens (dsDNA, nucleosome, Sm, Sm/RNP, ribosomes, histone, U1-snRNP, SS-A 60, SS-A 52, SS-B, Scl-70, PM/Scl, CENP-A/B, PCNA, Jo-1, M2, DFS-70 and f-Actin) in human serum. The ANA 18 LINE is intended as an aid in the diagnosis of systemic inflammatory rheumatic diseases in conjunction with other clinical and laboratory findings. The immunoassay is designed for manual professional in vitro diagnostic use. Diagnostic Relevance The detection of antibodies in patient samples is well established and plays an essential role in the diagnosis of systemic autoimmune diseases. The appearance of antibodies directed against components of the cell nucleus are characteristic features of systemic autoimmune diseases, especially systemic lupus erythematosus (SLE), Sjögren’s syndrome, progressive systemic sclerosis (PSS), mixed connective tissue disease (MCTD), rheumatoid arthritis (RA) and dermatomyositis. Description - Line immunoassay for the qualitative determination of IgG antibodies against nuclear and cytoplasmic antigens in human serum Format - Test strips coated with dsDNA, nucleosome, Sm, Sm/RNP, ribosomes, histone, U1-snRNP, SS-A 60, SS-A 52, SS-B, Scl-70, PM/Scl, CENP-A/B, PCNA, Jo-1, M2, DFS-70 and f-Actin Sample volume - 10 µL serum No. of determinations - 20 x 18