Automated film heat sealer can seal various SBS standard microplates, such as deep well plates, PCR plates, and other types of SBS standard plates. This system greatly improves the sealing eciency of the well plates. This system can be used for auto-matic sealing of well plates for various IVD reagents, such as the production of nucle-ic acid extraction reagent sealing steps, PCR diagnostic reagent sealing, PCR reac-tion system sealing, etc.