Automatic sample preparation system PrestoCHILL

laboratoryfor slide stainingfor histology

PrestoCHILL is an advanced cryoembedding system that provides pathologists with frozen sections of permanent-like quality. Its innovative technology reduces the freezing time to 30 seconds and prevents ice crystal formation through ultra-fast freezing. With PrestoCHILL, even fatty tissues can be easily frozen without distorting their delicate structures, resulting in a perfectly flat plane surface that can be smothly cut in the cryostat. Permanent-Like Quality When performing frozen sections, pathologists often embed extremely delicate tissues, such as the intricate honeycomb structures found in breast or fatty lymph nodes. Frozen sectioning usually gives poor results, as the water within the tissue creates ice crystals that enlarge and deform the cellular structure and morphology of the tissue. Milestone’s groundbreaking and ultra-fast freezing technology, enabled by its patented “face-down embedding” technique, provides an innovative and rapid solution to this challenge. The temperature of -40°C allows for extremely quick freezing, eliminating: freezing artifacts the creation of ice crystals the compression of tissue structure caused by extremely low temperatures the retraction of tissues Milestone’s patented technology permits the direct contact of the sample with the cold metal, giving the fastest freezing possible. This allows the user to achieve perfectly “flat plane” surfaces, reducing trimming time and creating frozen sections that can be easily cut.