Research assay kit EarlyTox™

cell viabilityapoptosiscell

The EarlyTox™ Cell Integrity Kit enables the differentiation of live cells from dead cells via fluorescent labeling. This is useful for the rapid quantification of cell viability when used with the SpectraMax® MiniMax™ 300 Imaging Cytometer or other fluorescence-based cellular imaging instruments. EarlyTox Cell Integrity Kit The EarlyTox Cell Integrity Kit is an optimized set of reagents that simplifies the identification of live and dead cells. It can be used to measure the effects of different treatments on cell viability and to evaluate toxic effects mediated through a variety of mechanisms, including apoptosis and necrosis. The kit is designed to work with many cell types, both adherent and non-adherent. The protocol's simple workflow and reagent performance make it amenable to high-throughput screening. Higher signal allows shorter exposure times for fast results Designed to work with many cell types Streamlined image acquisition and analysis on a single system Images of Untreated and Compound-Treated HeLa Cells (A) Untreated cells (left panel) are mostly alive, with red fluorescent nuclei. At an intermediate concentration of compound (center panel), there is a mixture of live and dead cells. At high compound concentration (right panel), most cells are dead, with nuclei labeled both red and green. Images were acquired on the SpectraMax® MiniMax™ 300 Imaging Cytometer. (B) Cells were identified as live (red masks) or dead (blue masks) using the Classification feature in SoftMax® Pro Software.