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The MEA2100-Mini-System is a miniaturized in vitro recording system. The state of the art power saving electronics allow to benefit from almost all advantages of the MEA2100 platform and still be able to operate the system continuously in the incubator. The system consists of a 60-channel headstage, featuring a sampling rate of 50kHz per channel at a 24bit resolution, as well as a 2-channel stimulator with basically arbitrary patterns. The digitized data is transfered from the headstage to a signal collector unit for up to four headstages. The signal collector unit is connected via an eSATA cable to the MCS-IFB interface board.