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Components -
96-well polystyrene microplate (12 strips of 8 wells) coated with a monoclonal antibody against human TL-1A
Human TL-1A Standard, lyophilized
TL-1A Detect Antibody
Standard Diluent
Streptavidin-HRP
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Adhesive Films
Describtion -
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human β-NGF. The Human β-NGF ELISA is for research use only. Not for diagnostic or therapeutic procedures.Tumor necrosis factor-like ligand 1A (TL1A), also called TNFSF15, is a member of the TNF superfamily. It is a homotrimeric 251 amino acid cytokine expressed from the TNFSF15 gene located at locus 9q32 on chromosome 9. The expression of this protein is inducible by TNF and IL-1 alpha. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor.
Format - 96-well strip plate
Storage - 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)
Shipping Condition - 4℃
Sensitivity - 3.09 pg/ml
Standard Curve Range - 31.25-2000 pg/ml
Spike Recovery Range - 86%-97%