Giant unilamellar vesicles preparation system Vesicle Prep Pro

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The Vesicle Prep Pro is the first product on the market for automated preparation of solvent-free giant unilamellar vesicles (GUVs). The GUVs are formed by means of electro-swelling. The benefits the Vesicle Prep Pro offers include: GUVs of homogeneous size (1 - 30 μm in diameter) Temperature control Adjustable parameters (temperature; current amplitude; frequency) Variety of lipids can be used Ideal for bilayer recordings and protein measurements Stable and reproducible GUVs Reusable ITO slides The Vesicle Prep Pro has been designed to keep the preparation process simple. This ensures stable and reproducible results. The chamber in which the GUVs are made is formed by ITO-coated glass cover slides so that vesicle formation can be monitored using a microscope. Integrated features, including flexible protocol design and temperature control, allow generation of GUVs from a wide variety of lipids, e.g. lipids with high charge or high phase transition temperatures. GUVs prepared with the Vesicle Prep Pro have proven ideal for investigations of biophysical properties of e.g. electrogenic transmembrane proteins, lipid raft formation, and protein-DNA interactions.