Rapid Vibrio cholerae test 501050

for cholerafor antigensfeces

Cholera epidemics, caused by V.cholerae serotype O1, continue to be a devastating disease of immense global significance in many developing countries. Clinically, cholera may range from asymptomatic colonization to severe diarrhea with massive fluid loss, leading to dehydration, electrolyte disturbances, and death. V. cholerae O1 cause this secretory diarrhea by colonization of the small intestine and production of a potent cholera toxin, Because of the clinical and epidemiological importance of cholera, it is critical to determine as quickly as possible whether or not the organism from a patient with watery diarrhea is positive for V.cholera O1. A fast, simplr and reliable method for detecting V.cholerae O1 is a great value for clinicians in managing the disease and for public health officials in instituting control measures. PRINCIPLE The Vibrio cholerae O1 Antigen Rapid Test Device (Feces) detects Vibrio cholerae O1 through visual interpretation of color development on the internal strip. Anti- Vibrio cholerae O1 antibodies are immobilized on the test region of the membrane. During testing, the specimen reacts with anti- Vibrio cholerae O1 antibodies conjugated to colored particles and precoated onto the sample pad of the test. The mixture then migrates through the membrane by capillary action and interacts with reagents on the membrane. If there is sufficient Vibrio cholerae O1 in the specimen, a colored band will form at the test region of the membrane.The presence of this colored band indicates a positive result, while its absence indicates a negative result. The appearance of a colored band at the control region serves as a procedural control,