Pulmonary infectious disease test kit

biomarqueursserumplasma

Krebs von den Lungen 6 (KL-6) is a mucin-like, high molecular weight glycoprotein expressed on the surface membrane of alveolar epithelial cells (AEC-II) and bronchiolar epithelial cells. It exists as a solubilized component in the pulmonary epithelial lining fluid by proteolytic cleavage. KL-6 serum concentration is elevated mainly because two mechanisms: Elevated pulmonary production due to diffuse hyperplasia of alveolar epithelial cells (AEC, called also pneumocytes). Sample Requirements 1. The serum is recommended to be collected by ordinary serum collection tubes or tubes with procoagulant. If it cannot be used immediately, it is recommended to be stored at 2-8℃ and the test should be completed within 24 hours. If the test cannot be performed within 24 hours, the sample needs to be frozen at -20℃ for 1 month. 2. Plasma is recommended to be anticoagulated with heparin or EDTA. If it cannot be used immediately, it is recommended to be stored at 2-8 ℃ to complete the test within 24 hours. If the test cannot be performed within 24 hours, the sample should be frozen at -20℃, valid for 1 month. 3. Samples containing sediment or flocculent material should be centrifuged (4000rpm, 10min) and then tested. 4. Samples must be returned to room temperature (10-30℃) before testing. Frozen samples should be completely thawed, rewarmed and mixed well before use. Do not repeatedly freeze and thaw. 5. Heat inactivated samples, hemolysis and other abnormal samples should be discarded.