NadPrep NanoBlockers (for Illumina®, NXT) is a universal blocking sequencing designed for use with Illumina's sequencing platform for the Nextera™ library. This product can bind to the Tn5 adapters sequences of the libraries, reducing non-specific binding between adapters, which enhances on-target rate, increasing the depth of enrichmen
Features
Single-tube universal: Capable of blocking adapter libraries with single or dual 6-10 nt indexes.
Efficient blocking: Significantly enhances the efficiency of captured data.
Stable performance: Excellent and consistent capture performance across different batches and sizes of panels.
User-friendly: Compatible with Nanodigmbio's liquid-phase hybrid capture system
Can NadPrep NanoBlockers be diluted for use? What is the maximum total library input that can be blocked?
No. They can effectively block a total library input of up to 6 µg during hybridization capture when starting with 500 ng/library and performing 12 multiplexing cycles.