A rapid test for the qualitative detection of IgG and IgM antibodies to Salmonella typhi (S. typhi) in human whole blood, serum or plasma. For professional in vitro diagnostic use only.
Typhoid fever is caused by S. typhi, a Gram-negative bacterium. World-wide an estimated
17 million cases and 600,000 associated deaths occur annually1. Patients who are
infected with HIV are at significantly increased risk of clinical infection with S. typhi2.
Evidence of h. pylori infection also presents an increase risk of acquiring typhoid fever. 1-
5% of patients become chronic carrier harboring S. typhi in the gallbladder.
The clinical diagnosis of typhoid fever depends on the isolation of S. typhi from blood,
bone marrow or a specific anatomic lesion in the facilities that cannot afford to perform this
complicated and time consuming procedure, Widal Test (also referred as Weil-Felix Test)
is used to facilitate the diagnosis. However, many limitations lead to difficulties in the
interpretation of the Widal test 3, 4.
In contrast, the Typhoid Rapid Test Cassette is a simple and rapid laboratory test. The test
simultaneously detects and differentiates the IgG and the IgM antibodies to S. typhi
specific antigen5 in whole blood, serum or plasma thus aid in the determination of current
or previous exposure the S. typhi.