DNA extracted from the blood of transplant donors or recipients is tested by NGS, and among histocompatibility antigens, HLA-A, -B, -C, -DRB1, -DQB1, etc are analyzed. It is a precision diagnostic panel that helps select the optimal donor by identifying alleles at high resolution
NGS-based histocompatibility test
In order to minimize side effects of organ and bone marrow transplantation, precedent histocompatibility genetic testing is performed using NGS technology. Simultaneously identifies 5 or 11 loci at high resolution to help select optimal donors.
Can be used in combination with histocompatibility gene antigen typing analysis software
HLAaccuTest™ can be used in combination with ‘EasyHLAanalyzer’, a histocompatibility analysis software. NGS data from tested reagents is analyzed automatically. Including the reading and clinical report preparation, all the steps are implemented in a one-stop process.
Auto-analysis based on the IMGT/HLA database
Application of a self-developed bioinformatical analysis pipeline