A personal super-resolution microscope that provides the same high resolution as the N-SIM S.
N-SIM E is a streamlined, affordable super-resolution system that provides double the resolution of conventional light microscopes. Combining N-SIM E and a confocal microscope allows you the flexibility to select a location in the confocal image, and easily switch to view it in super-resolution, enabling the acquisition of more detail.
Double the resolution of conventional light microscopes
The N-SIM E utilizes Nikon's innovative approach to "structured illumination microscopy". By pairing this powerful technology with Nikon’s renowned objectives (with unparalleled NA of 1.49) the N-SIM E nearly doubles the spatial resolution of conventional light microscopes to approximately 115 nm*, and enables detailed visualization of minute intracellular structures and their interactions.
Fast 1 sec/frame temporal resolution for super resolution imaging
N-SIM E provides fast imaging performance for Structured Illumination techniques, with a time resolution of approximately 1 sec/frame, effective for live-cell imaging.
Acquire larger fields of view
N-SIM E can acquire super-resolution images with a large field of view of 66 µm square. This larger imaging area enables very high throughput for applications/samples that benefit from larger fields of view, such as neurons, reducing the amount of time and effort required to obtain data.