For rapid and simple purification of cell-free circulating DNA from plasma/serum samples
Isolate all sizes of circulating DNA from plasma and serum samples
Isolate viral and bacterial DNA
Versatile plasma and serum input volumes
Concentrate circulating DNA into a flexible elution volume
Isolate inhibitor-free cell-free circulating DNA
Compatible with Streck Cell-Free DNA BCT® Tubes
Purification is based on spin column chromatography that uses Norgen’s proprietary resin separation matrix
Professional Tech Support with Senior R&D Scientist
Fast and Flexible Ordering Options (online, email, or phone)
Volume Discounts Available on Large Quantity Orders*
Plasma/Serum Cell-Free Circulating DNA Purification Kits
These kits provide a fast, reliable and convenient spin column method for the isolation of high quality, high purity and inhibitor-free cell-free circulating DNA (cfc-DNA) from plasma/serum sample volumes. The purified plasma/serum cfc-DNA is fully compatible with all downstream applications including PCR, qPCR, methylation-sensitive PCR and Southern Blot analysis, microarrays and NGS.
Background
Plasma/Serum cell-free circulating DNA (cfc-DNA) has the potential to provide biomarkers for certain cancers and disease states as well as fetal DNA in maternal blood. Currently, significant advancements are being made in utilizing cfc-DNA as biomarkers for the early diagnosis, prognosis and monitoring of therapy for several cancer types and autoimmune diseases. Cell-free mitochondrial DNA (cfmtDNA) is also under investigation for its clinical significance. This cfc-DNA is usually present as short fragments of less than 1000 bp.