Carcinoembryonic antigen (CEA) is an oncofetal glycoprotein primarily found in select tissues of a developing baby (fetus). CEA occurs at abnormally high levels in several benign disorders but may also indicate some malignant tumors, including those of the stomach, small intestine, colon, rectum, pancreas, liver, breast, ovary, cervix, and lung. Levels of CEA are significantly lower in colon tissue of adults, but can become elevated when inflammation or tumors arise in any endodermal tissue, including in the gastrointestinal tract, respiratory tract, pancreas and breast.
CEA is also expressed by epithelial cells in several non-malignant disorders, including diverticulitis, pancreatitis, inflammatory bowel disease, cirrhosis, hepatitis, bronchitis and renal failure. This fact has made it difficult to use serum CEA determination as a sensitive method for cancer screening. However, serum CEA levels have been useful in monitoring individuals for the recurrence of cancer.
Specification
Working range - 1.0-200.0 ng/mL
Reference range - <6 ng/mL
Storage condition - Cartridge: 2-30 ℃
Detection buffer: 2-8 ℃
Shelf life - 24 months