Prostate specific antigen (PSA) is a protein made by cells in the prostate gland. A neutral serine protease with chymotrypsin-like activity, PSA is composed of a single polypeptide chain of 237 amino acids. It is an intracellular glycoprotein containing 7-8% carbohydrate as a single N-linked oligosaccharide side chain.
PSA is exclusively synthesized by the prostate epithelium and primarily released into the semen. Normally very small amounts of PSA are secreted and detected in male blood. The elevated levels of PSA in male blood are known to be associated with some prostatic disorders such as prostatitis, benign prostatic hyperplasia (BPH) or prostate cancer.
Specification
Working range - 0.1-100.0 ng/mL
Reference range - <3 ng/mL
Storage condition - Cartridge: 2-30 ℃
Detection buffer: 2-8 ℃
Shelf life - 24 months