Mice Vogel test VTA 01

Vogel Test Apparatus or Vogel Test Anxiometer is used for screening of anxiolytic effects of drugs on small laboratory animals like mice and rat. The Vogel test is a conflict test has become a standard for fast screening the potential anxiolytic properties of drugs. In this procedure, the drinking behaviour is punished by mild electrical shocks leading to a significant reduction of water consumption in deprived animals. Drinking responses are then re-established by drugs with anxiolytic properties. Vogel test consists of a standard home cage for mice as well as rat associated with a grid floor. An electronic unit associated with a special nipple ensures the detection and counting of the licks reflecting the animal drinking behaviour. Orchid's Vogel Test Apparatus is designed to induce anxiety within a subject and monitor the degree of drug effect by the administration of a mild shock after 20 licks on a sipper tube. The shock is delivered through the sipper tube and is maintained for a selectable duration of 0.25 to 2.0 seconds. The intensity of shock is user adjustable. With the onset of the initial shock, Anxiometer begins a three minute testing session during which the total number of licks and shocks (administered with every 20th lick) is recorded on front panel counters. The performance of anti-anxiety drugs can be measured by comparing the drinking behaviour of punished drugged rats to the behaviour of punished non-drugged rats.