Microscope light source Mosaic 3

for optogeneticsLEDlaser

Mosaic 3 is a patented instrument platform built around a MEMS Digital Mirror Device (DMD). The DMD comprises an array of individually controllable micro-mirrors that can be switched “on and off”. DMD arrays contain hundreds of thousands to millions of micro-mirrors allowing precise control of illumination in user defined patterns or across multiple regions. These properties have made mosaic an exceptionally useful and versatile tool for optogenetic and photostimulation experiments. ​​​ Features and Benefits of Mosaic 3 Unlimited flexibility in shape, size, complexity of illumination mask Simultaneous illumination of multiple regions of interest Precise illumination of areas of interest that protects target specimen and fluorophore Zero delta acquisition time for true digital excitation Complementary illumination option enables on and off control in optogenetics studies Longest lifetime and lowest maintenance with semiconductor device Fluorescence Recovery after Photobleaching (FRAP) FRAP is the basis for many experiments that seek to determine processes that may be hidden by background fluorescence levels such as protein turnover, diffusion rates and many more. Applications & Techniques Fluorescence recovery shown for A. thaliana Mosaic 3 is a unique solution for FRAP providing user-defined illumination, or simultaneous illumination of multiple regions. Boost productivity and insights by capturing multiple measurements in a single experiment. Uncaging Mosaic 3 is ideal for experiments that require biomolecules to be uncaged and photoactivated into their active state.