The Imaris for Neuroscientists package enables 3D reconstruction of neurons and arborization analysis. It can resolve various structures, such as axons and dendrites, somas, dendritic spines, microglia, or astrocytes. It calculates a range of neuron-specific measurements, such as dendrite or segment length, orientation, diameter, branch level, spine density and spine shape analysis and classification.
In addition, Imaris for Neuroscientists is perfect for tracing blood vessels and getting measurements like segment length and total length, diameter, mean segment intensity and orientation of segments. In addition, Imaris for Neuroscientists is great for object tracking, plotting, group comparisons and provides a two-way interface for customization in Matlab, Java, or Python.
Tracing Neurons and Detection of Cells and Structures
Microscopy image analysis requires precise detection of multiple biological structures based on the initial signal saved as an image data. Object detection in Imaris will be quick and easy as users are guided within a wizard driven interface to create perfect models of their data. With our patented Torch™ tool and several performance improvements tracing neurons with Autopath or Autodepth in dense and thick samples is very efficient and becomes a unique experience.
Neuron Structure
Depending on their function and origin in the brain, neurons vary in shape and size. In addition, changes in neuron morphology can be indicative of various diseases or pathological conditions. The neuronal structure can be as well modified during learning or regeneration. Analysis of the neuronal branches and their structure is a valid neuroscience research tool