Transplantation organ preservation transport system LIVERguard™

liveron casters

In the mission-critical world of transplantation, where there is no margin for error, Paragonix delivers the most advanced technologies to support transplant teams around the world every day. Addressing the Risks of Cold Ischemia Time Cold ischemia time refers to the period of time during which a donor liver is cooled to maintain its viability until it can be transplanted into the recipient. The length of cold ischemia time may vary greatly, although prolonged cold ischemia time is traditionally associated with greater risk of complications after the transplant procedure. Research has linked longer cold ischemia times with poor outcomes, such as longer post-transplant hospital stays and a higher rate of primary graft nonfunction. ‍ Traditionally, donor livers destined for transplantation were placed into commercial-grade coolers filled with ice to transport it to the recipient. This method presents a multitude of uncontrolled variables that can also impact the function of the liver post-transplant. Clinical evidence has shown that the use of ice can expose donor organs to freezing temperatures, leading to irreversible cellular damage. The Paragonix LIVERguard is an Advanced Organ Preservation device specifically designed to standardize the variables of donor liver preservation, providing physicians with stable cooling technology driven by real-time data monitoring. Technological Advantage of Advanced Organ Preservation An FDA-cleared and CE-marked preservation device intended to protect the donor liver in transit Validated to maintain a consistent thermal environment for 40 hours