This RNase inhibitor is designed for use in RNA-sensitive applications such as RT-qPCR, cDNA synthesis and RNA sequencing, where the presence of even small amounts of RNase can be highly detrimental to RNA quality and experimental outcome.
Features
Superior protection leading to better performance of RNA-sensitive applications
Particularly suited to incorporation into saliva-based tests for SARS-CoV-2 detection
Inhibits eukaryotic RNases, including RNase A, B and C
Compatible with reverse transcriptases, RNA polymerases and Taq DNA polymerase
Stable up to 65°C for at least 30 minutes
Ribonuclease and phosphatase free
More Information
Ribonucleases (RNases) are found in all cell types and organisms, and their ubiquitous nature can be highly problematic in the lab. Contamination with even the smallest amount of RNase in an RNA sample is enough to completely destroy the RNA. RiboShield™ RNase Inhibitor is a recombinant human placental protein that blocks the activity of a wide range of ribonucleases, including RNase A, B and C, to reliably protect your RNA from RNase digestion.
RNase inhibitor with superior RNA protection
RiboShield™ RNase Inhibitor is designed for RNA-sensitive applications including RNA isolation, RT-qPCR, cDNA synthesis, and RNA sequencing, to shield your RNA from degradation and provide higher yields and better performance as a result.
The inhibitor binds noncovalently to RNases at a 1:1 ratio and with very rapid kinetics of association, guaranteeing immediate protection of your RNA. RiboShield™ RNase Inhibitor has been tested in RT-qPCR and offers the greatest RNA protection when compared to leading competitor products (see figure 1).