Inspection system for the pharmaceutical industry CUB-X

high-speed

The CUB-X is an innovative and versatile tablet inspection system, which can be used for OSD product & process development, as well as for IPC sample analysis and full batch inspection & sorting. It is equipped with novel spectroscopy and laser technologies allowing for high-speed highly accurate non-destructive measurement of tablet thickness, API’s mass fraction and moisture content. Key benefits Easy and fast product format change-over Easy process data exportation via OPC UA and/or batch reporting GAMP and CFR21 compliant data storage and software CE compliant Simple chemometric recipe preparation Expert assistance for chemometric models development The CUB-X can measure tablet mass fraction for multiple ingredients – including moisture – at speeds up to 20.000 tablets/h using NIR-SRS spectroscopy, while tablets can be sampled at speeds up to 400 tablets/h for measurement of mass, thickness, diameter/length and hardness. This allows sampled tablets to be analyzed for porosity, dosage, and content uniformity, while all tablets are analyzed for API mass fraction. EMBEDDED TECHNOLOGIES High-precision Tablet Laser Profiler A laser line-scanning sensor profiles each tablet, while passing under the sensor, measuring its thickness with a precision of 50 µm. The tablet laser profiler also verifies the correct position and orientation of the tablet on the conveyor belt before it passes under the NIR-SRS sensor. NIR-SRS spectroscopy Each tablet is inspected by the multipoint NIR-SRS (Near-Infra-Red Spatially Resolved Spectroscopy) probe at a high frame rate, allowing multiple spectral acquisitions per tablet.