The inverted HoloMonitor cell culture microscope gives you label-free, single-cell analysis on a population level. It works in real-time within a CO₂ incubator or hypoxia chamber. This lets you do long-term studies of in vitro cell cultures in a stable and physiologically relevant environment. HoloMonitor non-invasively quantifies more than 30 cellular parameters reflecting cell proliferation, cell migration and invasion, and cell morphology and differentiation.
Cell-friendly, long-term analysis
The HoloMonitor cell culture microscope is an incubator tolerant cell culture imager. This makes it suitable for long-term live cell analysis. Better yet, using quantitative phase-contrast microscopy, it images your cells with no labels or stains. When you place it in a CO₂ incubator, you can monitor your cell cultures under optimal conditions. Hence, HoloMonitor allows cell analysis for long periods of time, without having the imaging procedure or instrument affect your cells.
Single-cell analysis on a population level
HoloMonitor is a cell culture microscope, which means it images and analyzes cell cultures. However, each image it takes contains data on more than 30 cellular parameters on every single cell. Therefore, you can analyze your cell cultures not only at a population level but down to the single-cell level. The time-lapse images are automatically analyzed as your experiment goes on. Hence, it gives you graphs and scatterplots on single-cell and population data in real-time.
Reuse your cells after the experiment
HoloMonitor does not need labeling, stained or modified cells to be able to image them. The low-energy laser keeps phototoxicity to a minimum,