Myocardial infarction assay kit PATHFAST™ Myo

myoglobinplasmawhole blood

PATHFAST™ Myo is a product for in vitro diagnostic use with the in vitro diagnostic system PATHFAST™ for the quantitative measurement of Myoglobin in heparinized whole blood and plasma. The result obtained with the assay is used to assist in the diagnosis and especially in the exclusion of acute myocardial infarction. Myoglobin (Myo) is a low molecular weight, heme-protein found in both cardiac and skeletal muscle. Following myocardial necrosis associated with acute myocardial infarction (AMI), myoglobin is one of the first markers to rise above normal levels, increasing measurably above baseline within 1-3 hours post infarction, peaking at 6-12 hours and returning to baseline within 24-36 hours. In the absence of skeletal muscle trauma or other situations associated with a non cardiac related increase in circulating myoglobin (e.g. renal failure), measurement of myoglobin in blood has been used as an early marker of AMI. Several studies proved that the measurement of myoglobin can be used as a rapid and sensitive test in the early phase of AMI for its diagnosis in conjunction with the ECG and for exclusion of myocardial infarction in patients presenting with acute chest pain, especially after a further negative test one hour later.