Build Crystallization Screens with Ease
Crystallization hit optimization and custom screen creation are integral parts of crystallographic workflows. The FORMULATOR® is a specialized microfluidic liquid dispenser to create macromolecular crystallization screens. It can dispense up to 34 different ingredients. A 96-nozzle dispensing chip can dispense any volume of any ingredient of any viscosity into any well. It has broad viscosity compatibility necessary to handle various ingredients found in commercial screens.
Flexible Liquid Dispensing
Low volumes, down to 200 nL with no upper limit
Dispense a 100 μL, 3-ingredient, 96-well crystallization grid in 2.7 mins
Supports all microplate types, even VDX/Linbro plates
Easy Operation
Integrated barcode scanner automatically loads experiment and ingredient data
Bottle sensors know where ingredients are located
Design, Barcode, Scan, and Run
The only screen builder integrated with ROCK MAKER - Crystallization Software
Dispense Viscous and Non-Viscous Ingredients
At the core of the FORMULATOR is a patented microfluidic chip that measures and dispenses discrete volumes of liquid. The chip has 96 outputs, each with its own microfluidic valve cluster. Each valve cluster has two micro-diaphragms (200 nL and 2.5 µL) that fill and dispense up to three times per second. By combining multiple dispenses of each micro-diaphragm, the FORMULATOR can dispense any volume down to 200 nL.