Endobronchial valve bioprosthesis ZEPHYR®

sutureless

Zephyr® Endobronchial Valve The Zephyr® Endobronchial Valve is an endoscopic lung volume reduction therapy that has been proven to significantly improve lung function, exercise capacity and quality of life for emphysema patients across four randomized, controlled clinical trials and in 12,000 patients worldwide. In combination with its diagnostic companion products, it uniquely offers a prospectively proven method for predicting responders. It is also designed to be removable, preserving future treatment options for patients. The UK’s National Institute for Health and Care Excellence (NICE) has updated its guidance for endobronchial valves and now considers current evidence sufficient to support routine use. The change in NICE guidance is based on safety and efficacy data from multiple randomized clinical trials evaluating the Zephyr EBV, which has demonstrated clinical and quality of life benefits, and long-term safety for eligible patients. Using a standard bronchoscope, Zephyr valves are delivered to target airways using a flexible delivery catheter Once implanted, the one-way valve prevents airflow into the diseased region, while allowing trapped air and fluids to escape Reducing the volume of the diseased region may allow healthier regions to expand and function more efficiently