A single day sample to sequencing workflow for simultaneous enrichment and profiling of DNA variants, RNA fusions and gene expression levels from one sample input, as low as 10 ng
Kit containing ALL reagents (except indexes) for multimodal (DNA and RNA) sequencing; Custom panel for a total of 192 reactions to process 96 samples
Features
Complete system to go from total nucleic acids to a sequencing-ready library using a single-day workflow
Error correction with Unique Molecular Indices (UMIs) to enhance NGS panel sensitivity
QIAseq enrichment technology overcomes the limitations of traditional amplicon approaches on amplicon size and primer multiplexing
Unique Dual Indices (UDIs) to reduce sample index hopping
Sample to Insight solution for consolidated targeted DNA and RNA sequencing
Product Details
QIAseq Multimodal Panels have been developed for consolidated targeted DNA and RNA enrichment and analyses. Unlike other available approaches, QIAseq Multimodal Panels do not require 2 separate workflows for DNA and RNA analysis – saving time and conserving samples that are of limited availability.
Custom panels can be designed to target exonic regions of genes, hotspots or SNPs, intronic and promoter regions, known gene fusions based on characterized breakpoints, or to discover novel fusions.
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Principle
Recent advances in NGS chemistries, platforms, and bioinformatics pipelines are enabling users to efficiently interrogate biological samples for changes in DNA and RNA