Infection test kit RIDASCREEN®

IgGserumfeces

For in vitro diagnostic use.The RIDASCREEN® Toxocara IgG test is an enzyme immunoassay for the qualitative determination of IgG antibodies against Toxocara canis in human serum. The test should be used for confirmation purposes when there is a suspected case of toxocariasis. General information: Toxocariasis is an infection caused by migration of roundworm Toxocara larvae to organs and tissues. Infected cats or dogs excrete eggs with their feces. Humans are infected by ingestion of eggs from the environment (studies of United Kingdom’s parks showed 24 % of soil samples with eggs) or by direct contact to infected animals. After their ingestion, eggs free in the gut the larvae, which go across gut’s walls and migrate to different organs (liver, lungs, CNS, eyes, muscles) through the circulatory system. Incubation period may range from weeks to months, depending on infection intensity and patient sensibility. Distribution is probably world wide. In United States and United Kingdom the disease has been target of greater attention, but there is probably not less prevalence in other countries. The grave form occurs sporadically, affecting rather children from 14 to 40 months old, though occurs even to older children. Few times, adults are infected. That lower incidence in adults and older children is rather related with a less exposition to the disease. Test principle: Purified antigens are coated to a microwell plate. Antibodies in the patient samples bind to the antigens and are determined during the second step by using enzyme-labelled Protein A (the conjugate).