Enterovirus test kit RIDA®GENE

for gastrointestinal infectionsclinicalstool

For in vitro diagnostic use. RIDA®GENE Enterovirus is a multiplex real-time RT-PCR for the direct qualitative detection of Enterovirus from human stool samples and cerebrospinal fluid (CSF). RIDA®GENE Enterovirus real-time RT-PCR is intended for use as an aid in diagnosis of infections caused by enteroviruses (poliovirus, echovirus, coxsackievirus, human enterovirus 70/71). General information: Enteroviruses belong to the family of Picornaviridae and according to the current classification enteroviruses are divided into 15 species (enterovirus A-L and rhinovirus A-C), whereby the species enterovirus E-L are not described as human pathogenic.The species enterovirus A includes the human enteroviruses A and the coxsackie viruses A, whereas the enteroviruses B include the human enteroviruses B, the coxsackie viruses B and also the echoviruses. Furthermore, the human enteroviruses C, the coxsackie viruses C and the polioviruses are part of the species enterovirus C. Enteroviruses mainly infect infants and small children and are transmitted via the fecal-oral route but also sometimes by droplet infection and contaminated water. Most enterovirus infections are asymptomatic or present with mild cold-like symptoms. Though, due to the multitude of enterovirus species the clinical presentation in severe symptomatic diseases is of broad variety. Severe enterovirus infections are poliomyelitis, hand-foot-and-mouth disease, meningitis and myocarditis. Polioviruses are single-stranded RNA (ss-RNA) viruses and before their partial eradication they were distributed worldwide. Besides mild symptoms such as fever and cough, poliovirus can also cause poliomyelitis.