Gastrointestinal infection test kit RIDA®GENE

adenovirusrotavirusastrovirus

For in vitro diagnostic use. RIDA®GENE Viral Stool Panel II is a multiplex real-time RT-PCR for the direct, qualitative detection and differentiation of rotavirus, adenovirus 40/41 and astrovirus in human stool samples. The RIDA®GENE Viral Stool Panel II multiplex real-time RT-PCR is intended for use as an aid in diagnosis of gastroenteritis caused by rotavirus, adenovirus 40/41 and astrovirus, respectively. General information: Acute Gastroenteritis is one of the main causes of morbidity and mortality worldwide. Especially in children, enteral viruses are the primary cause of gastroenteritis. In the US, viral infections cause approximately 30.8 million cases of gastroenteritis, yearly. The most important pathogens causing diarrhea are rotavirus, adenovirus and astrovirus. Rotaviruses belong to the Reoviridae familiy of non-enveloped icosahedral double-stranded RNA (dsRNA) viruses. Symptoms of rotavirus infection are usually vomiting, watery diarrhoea and abdominal pain. The virus is transmitted by the fecal-oral route through contaminated hands and objects. Rotavirus is the main cause of diarrhoea in children aged under five and is responsible for the death of an estimated 611,000 children worldwide each year. Rotaviruses are classified in seven serogroups A – G, whereby the viruses of serogroup A are of major epidemiologic importance. Astroviruses are single-stranded (ssDNA) viruses and belong to the family of Astroviridae. An astroviral-dependent Gastroenteritis is primarily manifested by dirarrhoea, but can also be accompanied by vomiting and fever.