For in vitro diagnostic use. The RIDASCREEN® Taenia solium IgG test is an enzyme immunoassay for the qualitative determination of IgG antibodies against Taenia solium and its cysticerci (bladder worms) in human serum. The test should be used for confirmation purposes when there is a suspected case of infection with Taenia solium.
General information:
Cysticercosis is a disease characterized by the harboring of the larval form (cysticercus) of Taenia solium in any tissue or organ. Although many sites of infection have been documented, the larvae are often found associated with the central nervous system. Presence of the cysticerci in the brain may cause increased cranial pressure, seizures and altered mental states. The disease is acquired by ingestion of T. solium eggs out of which the larvae slip in the intestine. This may happen from a number of different routes such as food contaminated with feces or contaminated water. Additionally, humans can be infected with the tapeworm itself by uptake of larvae containing meat. If eggs are set free in such tapeworm carriers, an endogenous infection with cysticercus will happen. Diagnosis of cysticercosis usually requires multiple methods such as radiography and serology. Although use of specific antigens has helped to increase ELISA’s sensitivity and specificity, significant cross reactions with other diseases (such as echinococcosis) is still a problem. All positive serology samples should be confirmed by an other test method such as the western blot.