Respiratory infection test kit RIDA®GENE

bacteriaLegionella pneumophilasputum

For in vitro diagnostic use. RIDA®GENE Legionella is a multiplex real-time PCR for the direct, qualitative detection and differentiation of Legionella pneumophila and Legionella spp. from human tracheal secretion, sputum and bronchoalveolar lavage fluid (BAL). The RIDA®GENE Legionella multiplex real-time PCR is intended for use as an aid in diagnosis of respiratory infections caused by Legionella. General information: The Genus Legionelle belongs to the family of Leginellaceae and can be divided in over 40 species with more than 70 serogroups. Legionella are facultative, intracellular gram-negative bacteria and their infectious peak occurs during the summer months and early fall. One differentiates between community-acquired infections, travel-associated disease and hospital-acquired infections. In the US, the mortality rate of hospital-acquired Legionella infections is between 15 – 20%. In Europe, 12% of all Legionella infections are fatal. Of the broad variety of Legionella species, two human pathogenic species are of importance. L. pneumohila primarily causes Legionnaire’s disease and L. longbeachae results in Pontiac fever. Pontiac fever is an acute self-limiting influenza-like diseases, however, no pneumoniae occurs. About 7% of people infected with Legionella develop Pontiac fever.3 L. pneumophila has 16 serogroups, whereas about 70% of all Legionella infections in Europe are due to L. pneumophila serogroup 1. Other Legionella species that result in an infection are for instance L. micdadei, L. bozemanii, L. dumoffii and L. longbeachae.