Respiratory infection test kit RIDA®GENE

bacteriaMycoplasmaChlamydophila pneumoniae

For in vitro diagnostic use. RIDA®GENE CAP Bac is a multiplex real-time PCR for the direct qualitative detection and differentiation of Chlamydophila pneumoniae (Chlamydia pneumoniae), Legionella pneumophila, and Mycoplasma pneumoniae in human bronchoalveolar lavage (BAL). The RIDA®GENE CAP Bac multiplex real-time PCR is intended to use as an aid in diagnosis for community-acquired pneumonia (CAP) caused by Chlamydophila pneumoniae, Legionella pneumophila, or Mycoplasma pneumoniae. General information: Community-acquired pneumonia (CAP) is the most frequently recorded infectious disease worldwide and is the infectious disease which most frequently leads to death in Western nations. In Germany, there are up to 600,000 cases of CAP annually, and the mortality varies between 0.6 % and 14 % depending on whether CAP is outpatient or inpatient. Bacteria are the most frequent pathogens of CAP, and a distinction is drawn between typical and atypical pathogens. Atypical bacteria cannot be cultivated in a regular culture of sputum or blood and also cannot be visualized by gram staining. This makes it difficult to detect atypical CAP bacteria since standard methods generally make identification impossible. The most frequent atypical CAP bacteria include Mycoplasma pneumoniae (M. pneumoniae), Legionella spp., and Chlamydophila pneumoniae (C. pneumoniae). Up to 20 % of outpatient pneumonias are triggered by M. pneumoniae. M. pneumoniae is a highly infectious bacterium without a cell wall that is primarily transmitted in the air through droplets or by direct or indirect contact through smear infections.