Parainfluenza test kit RIDA®GENE

for respiratory infectionsclinicallaboratory

For in vitro diagnostic use. The RIDA®GENE Parainfluenza test, performed on Roche LightCycler® 480 II, is a multiplex real-time RT-PCR for the direct qualitative detection and differentiation of parainfluenza 1, parainfluenza 3, and parainfluenza 2/4 RNA in untreated human nasal/throat swabs from persons with signs and symptoms of acute respiratory infection. The RIDA®GENE Parainfluenza test is intended to support the diagnosis of parainfluenza (parainfluenza 1, parainfluenza 3, and parainfluenza 2/4) infections in patients with symptoms of respiratory infection in connection with other clinical and laboratory findings. Negative results do not rule out infection with parainfluenza virus (parainfluenza 1, parainfluenza 3, and parainfluenza 2/4) and should not be used as the sole basis for diagnosis. The product is intended for professional use. General information: Human parainfluenza viruses (HPIVs) are enveloped, single-stranded RNA viruses from the family Paramyxoviridae. They can cause a number of respiratory illnesses, by initially infecting the pseudostratified mucociliary airway epithelium of the nose and oropharynx before spreading to the large and small airways. HPIVs are the second leading cause of hospitalizations in children under age 5 and are responsible for up to 17 % of hospitalizations. HPIVs can be divided genetically and antigenically into four serotypes that can infect humans: HPIV-1, HPIV-2, HPIV-3, and HPIV-4. HPIV-1 and -3 belong to the genus Respirovirus, while HPIV-2 and -4 are classified in the genus Rubulavirus.