Growth medium reagent ExCellerate B

for researchclinical

Media for the ex vivo culture of B lymphocytes under xeno-free conditions. Key Benefits Robust B cell expansion under xeno-free conditions Facilitates the isolation and expansion of B cells from peripheral blood Compatible for culturing B cells from multiple species Supports target antigen-specific B cell clonogenicity Supports culture of mouse B cell hybridoma cell lines for antibody production Why Use ExCellerate B Cell Media? B lymphocytes (B cells) play an essential role in the humoral component of the adaptive immune response. Following exposure to a pathogen or foreign material, B cells produce and secrete antibodies that circulate through the body and bind to specific pathogens, marking them for destruction. B cells also contribute to cellular immunity by maintaining immune homeostasis, including the regulation of T lymphocyte activation and expansion. Diseases or abnormalities that affect B cells have been shown to result in immunodeficiencies, autoimmunity, and cancer. Continued progress in basic and clinical B cell research is crucial for further understanding human health and disease. ExCellerate B Cell Media is formulated and optimized for the ex vivo culture of B lymphocytes under xeno-free conditions. Unlike traditional serum-containing media, ExCellerate B Cell Media provides a stable and optimized culture environment, void of non-human animal-derived products, that facilitates the isolation and expansion of B cells from peripheral blood. This media supports target antigen-specific B cell clonogenicity as well as robust culture of mouse B cell hybridoma cell lines for antibody production.