The Radnoti Isolated Lung System permits a wide variety of experimental formats to be explored. Constant pressure and constant flow perfusion can occur in both re-circulating and non-re-circulating modes.
Components Included With the System:
High-tech lung chamber
Sturdy, adjustable four bar stand.
Membrane oxygenator for solutions containing proteins or blood
Two water-jacketed reservoirs
Bubble traps to reduce endothelial damage caused by large gas bubbles
Manifolds for water, gas and perfusate control.
Inline pressure transducers to measure perfusion pressure
Pressure sensors are used to determine inspiration and expiration pressures and the gasses passed into the lung are humidified using a gas chamber.
A variable speed and volume respirator delivers humidified air or other gasses to the lungs (positive pressure) or creates a cycling negative/positive pressure change in the lung chamber (negative pressure).
Re-circulating, constant temperature bath for temperature control.
Peristaltic pump for recirculating of solutions and to maintain a constant pressure head or flow.
The lung cannula is attached to a force transducer with a +/- 5 volt readout for experimenters interested in measuring lung edema.