Monkeypox detection kit FastPlex

for infectious diseasesvirusserum

Monkeypox virus (MPXV) is an endemic zoonotic orthopoxvirus (OPX) found in West and Central Africa. The majority of human monkeypox (MPX) infections are reported from the Congo Basin in the Democratic Republic of Congo (DRC). MPXV is transmitted to humans from a primary zoonotic source, and it is also capable of human-to-human transmission. While the animal reservoir of MPXV remains unknown, several genera of African rodents (Cricetomys, Graphiurus, Funiscirurus) have been identified as potential reservoirs responsible for the transmission and maintenance of the virus. Contact with wildlife, often occurring in rural communities in the DRC that rely on bushmeat as a protein source, is believed to increase the risk of human infection with MPXV. The FastPlex Monkeypox Real Time PCR Detection Kit is designed for the qualitative detection of MonkeyPox virus (MPXV) DNA in serum or lesion exudate samples. It utilizes real-time polymerase chain reaction (RT-PCR) combined with Taqman fluorescent probe technology for the qualitative detection of MonkeyPox virus DNA. The MPXV F3L gene DNA detection probes are fluorescently labeled with FAM, the MPXV B6R gene DNA detection probes are fluorescently labeled with HEX, and the internal control detection probe is fluorescently labeled with ROX or Cy5. Positive results indicate the presence of MPXV DNA; however, clinical correlation with patient history and other diagnostic information is necessary to determine the patient's infection status. Positive results do not exclude the possibility of bacterial infection or co-infection with other viruses. The detected agent may not be the definitive cause of the disease.